Tavneos Liver Deaths: Japan Reports 20 Fatalities From Amgen-Kissei Vasculitis Drug
Kissei Pharmaceutical reports 20 deaths among Japanese patients treated with Tavneos (avacopan), a vasculitis drug. Twenty-two cases of vanishing bile duct syndrome were identified, with 13 deaths. The FDA has proposed withdrawal; Europe's EMA is reviewing. Here is what is happening in Japan, the US, and Europe—and what it means for ANCA vasculitis patients.