Researchers at Showa and Kansai Medical Universities grew mesothelial-like cells from human iPS cells to repair the peritoneum, the membrane that wears out and ends peritoneal dialysis. A look at the mouse proof-of-concept and why Japan's PD rate is so unusually low.
Japan's iPS cell therapy already treated fresh spinal injuries. Now a Keio University team is preparing a trial for the far harder chronic phase, where more than 100,000 patients have long been told regeneration simply isn't possible.
A Japanese biotech threaded a catheter into a failing heart and delivered iPS-derived muscle without opening the chest. Inside the world's first trial of its kind.
For 15 years, donor cells vanished when grown across species. A Tokyo-Stanford team found why: the host embryo's first immune cells were eating them alive. The path to lab-grown organs, explained.
Researchers at the University of Tokyo and Chiba University have developed ETE, a method that mass-produces hundreds of thousands of uniform cell-loaded capsules using only a bench-top vortex mixer and temperature control. A look at why it lowers the barrier for drug discovery and regenerative medicine, and how it compares with America's organoid industry.
A meniscus regeneration technology developed at Japan's Institute of Science Tokyo has been approved as Seibiscus, the country's first regenerative medicine product for meniscus injury. We explain how it uses a patient's own stem cells to repair the knee, what the Phase III trial showed, and how it compares with regenerative medicine ventures in South Korea and the US.
Kyoto University spinoff Toregem Biopharma kicks off Phase 2 trials this summer for TRG035, the world's first regenerative tooth drug, after raising an additional ¥850 million ($5.3M). Twenty-four pediatric patients with severe congenital tooth agenesis will receive the antibody. Here is what the deal tells us about Japan's deep-tech biotech funding stack — and how a super-aging society is becoming a uniquely positioned market for medical innovation.
On May 20, 2026, Japan added three ultra-expensive regenerative medicines to public insurance coverage: Amshepri (world's first iPS cell-derived drug, for Parkinson's), Akugo (stem cells for traumatic brain injury), and Zolgensma Intrathecal (gene therapy for SMA patients aged 2+). Prices range from 55 million yen ($352K) to 167 million yen ($1.06M). We explain why these drugs cost so much, how Japan's high-cost medical expense system shields patients, and whether prices might fall over time.