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#Startup

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Tech & Science

iPS Cell Diabetes Cure: Japan's Orizuru Therapeutics Launches Clinical Trials to Eliminate Insulin Injections

Japanese startup Orizuru Therapeutics has begun clinical trials transplanting iPS cell-derived islet cells into diabetes patients. The first-ever transplant surgery succeeded in February 2025, with company-sponsored trials planned in Japan and the US. Over a decade after Professor Yamanaka's Nobel Prize, Japan's regenerative medicine enters the practical stage.

Tech & Science

Space Safety Patrol: Japan's Astroscale Pioneers Orbital Debris Inspection as Space Junk Crisis Deepens

Japanese space startup Astroscale has announced its ISSA-J1 mission to realize a 'space safety patrol' service in orbit. As the space debris crisis intensifies with over 130 million pieces of junk circling Earth, this article explores how Astroscale's first-mover advantage in on-orbit servicing compares to rivals like ClearSpace and SpaceX, and what it means for Japan's growing space industry.

Business & Finance

302nm UV Laser for Quantum Computers: Japan's Oxide Ships the Heart of Neutral-Atom Machines

Oxide Corporation, an optical crystal maker in Hokuto, Yamanashi, began selling Frequad-K, a 302nm UV laser source for quantum computers, on March 9, 2026. The wavelength is what excites ytterbium atoms into the Rydberg states neutral-atom machines need, and the first unit went to a domestic customer. We look at why 95% world share in semiconductor wafer inspection crystals transfers to quantum, and at the 436nm quantum communications laser Oxide shipped to LQUOM in July.

Life & Lifestyle

Rice-Based Alternative Meat: Japan's Koji Mycoprotein Goes Into Production

Agro Ludens started mass-producing CoMeat, a rice-derived mycoprotein made with koji fermentation, at its Nasu plant in Tochigi in April 2026. It uses processing-grade rice, not table rice, and Japan's agriculture ministry approved mycoprotein as a new-market rice use in March. Plus: Japan's swing from rice shortage to rice glut, Beyond Meat down 99%, and why JR East is now farming.

Business & Finance

RWA Working Group: Ethereum Japan Launches Industry Standards for Corporate Blockchain Adoption

On March 9, 2026, Ethereum Japan launched the Digital Assets Working Group to define practical standards for corporate RWA and stablecoin use: access control, accounting, KYC/AML, audit readiness. Six firms joined, with Allied Architects as secretariat. Plus where the $33.5 billion RWA market actually stands, and Japan's crypto bill clearing its Upper House committee on July 14.

Business & Finance

3D-Printed Houses Go Two-Story: Japan's Construction Startups Tackle Labor Crisis with Printing Technology

Japan's first two-story 3D-printed house "Stealth House" has been completed in Miyagi Prefecture, built by startups KIZUKI and ONOCOM with 20+ collaborating companies. As Japan's construction industry faces a severe labor shortage with 200,000+ fewer workers since 1997, multiple firms including Serendix and Lib Work are accelerating 3D concrete printing technology. We compare with U.S. giant ICON, explore Japan's strict building code compliance, and examine cost advantages.

Tech & Science

Gas Hybrid Rocket TVC: Japan's Chiba Tech Achieves World-First Ground Combustion Test for Low-Cost Space Access

Chiba Institute of Technology has achieved the world's first ground combustion test of thrust vector control (TVC) using a gas hybrid rocket. Part of the Hestia Project, which aims to launch small satellites via balloon-based "Rockoon" method, this breakthrough demonstrated successful thrust vectoring at 2.0 kN over 8 seconds — opening a new path for affordable space access.

Tech & Science

Sakana AI Hits $2.65B Valuation: Japan's Most Valuable Unicorn Charts Its Own AI Future

Sakana AI, the Tokyo-based startup founded by former Google researchers, has raised $135M to reach a record $2.65B valuation — making it Japan's top unicorn. Citibank made its first-ever strategic investment in a Japanese company through this round. With backing from the CIA's venture arm and Google, Sakana is spearheading Japan's push for sovereign AI.

Business & Finance

Wolt Exits Japan: Why Finland's Beloved Delivery App Lost the Food Delivery War — And What It Reveals About Cracking the Japanese Market

On March 4, 2026, Finland-born food delivery service Wolt ended all operations in Japan after six years. Despite being loved for its god-tier customer support and elegant Nordic design, Wolt couldn't break through the Uber Eats/Demae-can duopoly that controls 90% of the market. We analyze why Wolt lost, what delivery workers face next, and what foreign tech companies need to succeed in Japan.

News, Society & Economy

Satellite Constellation: Japan's $1.8B Defense Ministry Space Surveillance Network Launches with 7-Company Private Sector Alliance

Japan's Ministry of Defense has signed a landmark $1.8 billion contract for a satellite constellation project. A special purpose company "TriSat Constellation," formed by Mitsubishi Electric, SKY Perfect JSAT, and Mitsui, will lead the effort alongside domestic space startups like Synspective and iQPS. A deep dive into Japan's pivotal shift in space defense strategy.

Tech & Science

Liquid Lens Glasses Revolution: Japanese Startup ViXion's Autofocus Eyewear Corrects Myopia, Farsightedness, and Presbyopia Automatically

A revolutionary pair of glasses born in Japan uses liquid lens technology to automatically adjust focus for myopia, farsightedness, and presbyopia. Developed by ViXion, a HOYA spinoff, the ViXion01S weighs just 33g and runs for 15 hours. With over $3.6 million raised in crowdfunding and a top government tech award, we explore this next-gen autofocus eyewear and the future of vision correction technology.