For 15 years, donor cells vanished when grown across species. A Tokyo-Stanford team found why: the host embryo's first immune cells were eating them alive. The path to lab-grown organs, explained.
A University of Tokyo-led team has produced the first high-precision genome of the Greenland shark, the longest-lived vertebrate. Changes in a linker histone and the ferritin gene offer the first real clues to its ~400-year lifespan, and to human aging.
Akita Prefecture has adopted environmental DNA surveys that estimate whether bears passed within 1km upstream in the past 24 hours from a single glass of river water. We explain how it works, its limits, and how it compares with grizzly-detection efforts abroad.
Kagawa, Japan's self-styled udon prefecture, throws away thousands of tons of noodles a year. Two teams found wildly different uses for the waste: a small factory that turns it into electricity, and a professor who turns it into surprisingly tough paper grown by microbes, now made at a welfare facility for Marugame's traditional fans.
In the American South, kudzu is a notorious invasive weed. In Japan, its flower yields tectorigenin, a supplement compound. A RIKEN team has now decoded how the flower makes it and brewed it in yeast, with no kudzu required.
A meniscus regeneration technology developed at Japan's Institute of Science Tokyo has been approved as Seibiscus, the country's first regenerative medicine product for meniscus injury. We explain how it uses a patient's own stem cells to repair the knee, what the Phase III trial showed, and how it compares with regenerative medicine ventures in South Korea and the US.
Kyoto University spinout Toregem Biopharma will begin Phase 2 trials of TRG035, the world's first tooth-regeneration drug, in summer 2026, dosing 24 children with congenital tooth agenesis. A pre-Series C round of ¥850 million brings cumulative funding, grants included, past ¥4.6 billion. A look at how Japan's university-biotech funding stack works, and why a super-aged society may produce this kind of innovation first.
Yamada Suisan and Japan's fisheries research agency put fully farmed eel on public sale for the first time on May 29. After cutting glass-eel production cost from 40,000 to 1,800 yen, the country aims to end wild-juvenile dependence by 2050.
Japanese telecom giant NTT runs a land-based shrimp farm in Iwata, producing 180 tons/year and capturing the largest domestic share. A deep dive into the 10-year plan to free Japan from its 90% shrimp import dependence, plus how it stacks up against Norway and Singapore.
A Japanese research team led by Gakushuin University has discovered Mitorubin, a plant-derived compound that simultaneously increases mitochondrial quantity and function. The compound improved heart function in aged mice and extended median lifespan by about 40% in obese mice on a high-fat diet — a distinct approach from US longevity biotech, NAD supplements, and senolytics.
In 2012, the Sankei Shimbun reported a biofuel revolution centered on Enomoto algae, a hyper-growth Botryococcus bred by Kobe University spin-off G> under Professor Taira Enomoto. Heavy-industry giant IHI joined biotech venture Neo-Morgan Laboratory to commercialize it, with then-CEO Tomohiro Fujita declaring he wanted to cut the price to one-tenth within ten years. Fourteen years later, the joint venture has dissolved, but the algae fueled the world's first flight on SAF meeting ASTM D7566 Annex 7, and a Japanese-led 5-hectare facility in Malaysia is now the largest of its kind on Earth. Did the promise come true, or is the dream over?