Basic Research & Academia

Fundamental science from Japanese universities and national research institutes.

195 Articles in this topic

All195 stories in Basic Research & Academia

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Technology

Photothermal Cancer Therapy: Tohoku's AI-Designed Protein and 0.5 mm Laser Endoscope

Tohoku University and Air Water went after the two bottlenecks that have kept photothermal cancer therapy in the lab for twenty years. IDP1, an artificial protein designed with AlphaFold, kept nanoparticles circulating for 150.5 minutes against 17.8 for PEG, and a 0.5 mm endoscope that fits inside a 16-gauge needle fired an 808 nm laser from inside the tumor at 28 percent less power. In mice, the tumors were gone within 14 days. How that compares with US trials already running in humans.

Technology

Ammonia Synthesis Catalyst: Japan's Air-Stable Electrene Runs at 300°C and 9 Atmospheres

Researchers at the Institute of Science Tokyo have created a surface electrene: a crystal whose outermost layer is a sheet of loose electrons, with a work function lower than cesium. It survives open air because nitrogen caps it, then leaves as ammonia. Here is what it means for green fertilizer, and how it compares with the electrochemical routes pursued in China, Europe and the US.